The Thresholds of Caprini Score Associated With Increased Risk of Venous Thromboembolism across Different Specialties: A Systematic Review

Proper risk assessment remains an important but often challenging part of venous thromboembolism (VTE) prophylaxis. One the known models used worldwide is Caprini score, which has been tested in different medical and surgical specialties. The primary objective this systematic review was to identify appropriate thresholds score that are associated with increased VTE across An electronic search MEDLINE Cochrane Library performed on March 1, 2022, according a prespecified registered protocol (CRD42022311755). Studies reported nonsurgical (medical) patients admitted hospital, individual assessed by correlation between incidence were included analysis. outcome combined any symptomatic or asymptomatic deep superficial vein thrombosis pulmonary embolism definition original study. A meta-analysis not due highly heterogeneous data qualifying publications. total 4562 references identified, 202 articles for eligibility. 68 studies enrolled 4,207,895 patients. cohorts varied profile mixed medical, coronavirus disease 2019 (COVID-19), cancer, burn, trauma orthopedics, urology gynecology, critically ill, variety other (vascular, general, head neck, thoracic, plastic). In all cohorts, significant increase observed scores 5 higher. 3 4, high rate detected only COVID-19 (4.5%), (5.3%), ill (5.5%) most 7 higher, 9 11 12 higher dramatically rates. COVID-19, trauma, vascular, thoracic surgery rates also (from 13% 47%). specific suggested cohorts. well-studied model illnesses. when reach Further needed validate categories illnesses have (obstetrics, bariatric surgery, neurosurgery, transplantation, etc) establish thresholds.